In 1995 Drs. David Benton, Rebecca Griffiths and Jurg Halier studied 125 young adult females for two months to determine if Thiamine (vitamin B1) had any correlation between the subjects and moods.
Benton et al provided each of the young women with a multi-vitamin containing 50 mg of thiamine or a placebo every day over the 60 day period. Before and after taking the tablets, mood, memory and reaction times were measured and monitored. They determined that there was a significant correlation between mood and thiamine status, as judged by transketolase activation.
What is particularly interesting is that all positive influences reported took place in subjects whose thiamine status, according to traditional criterion, was inadequate. An improvement in thiamine status was reported as being associated with being much more clearheaded, composed and energetic. It appeared, however, to have no effect on the improvement of memory. However, reaction times were reported to be much faster following the supplementation period.
This study is evidence that often first symptoms associated with a sub-clinical intake of micro-nutrients are psychological. It coalesces with a series of double-blind placebo controlled studies that report, in a least some of the population, that micronutrient supplementation is associated with improved mood, (Heseker et al 1990; Smidt et al 1991; and Benton et al 1995b).
The effect of supplements for increased scores on intelligence tests have been demonstrated by Botez et al 1984; Benton and Roberts 1988; Benton and Buts 1990; Benton and Cook 1991 and Schoenthaler et al 1991a,b. Nutritional supplementation has been shown to be effective for the improvement of memory by researchers Bonke and Nickel 1989 and Deijen et al 1992. While, Benton and Cook in 1991 established the importance of supplementing diet for attention deficits, Bonke and Nickel’s research in 1989 showed improvement in hand-eye coordination by reducing nutritional deficiencies through vitamin and mineral supplementation.
Certainly when considering vitamin deficiency, thiamine is one vitamin that must be acknowledged as extremely important for mood and cognitive function.
The human body stores only small amounts of vitamin B1. Therefore, there is great risk to mood stability and brain health if intake is reduced for only a few weeks . It is well documented that Korsakoff’s psychosis, a reflection of brain lesions caused by thiamine deficiency, is characterized by an inability to form new memories, apathy and emotional blandness. And, post-mortem brains tend to show that a deficiency of thiamine is sufficient to damage the brain similar to damage shown with Korsakoff’s psychosis in more instances than originally thought.
QuietMinds Nutritional Supplements addresses potential thiamine deficiencies by contributing 5mg of thiamine mononitrate, vitamin B1, in every eight capsule dosage.